STRINGSTRING
rpoE2 rpoE2 MMP0440 MMP0440 spt5 spt5 rps27ae rps27ae MMP0442 MMP0442 rps24e rps24e rpoA1 rpoA1 MMP0248 MMP0248 rpoA2 rpoA2 MMP0415 MMP0415 rpm rpm
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rpoE2DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (58 aa)    
Predicted Functional Partners:
MMP0440
DNA-directed RNA polymerase subunit E'.
  
 
 0.999
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
   
 
 0.999
rps27ae
SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family.
  
    0.993
MMP0442
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
    0.961
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.959
rpoA1
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.876
MMP0248
DNA-directed RNA polymerase related protein.
   
  
 0.866
rpoA2
RNA polymerase, A/beta'/A' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.862
MMP0415
Eukaryotic protein kinase:Glycoprotease (M22) metalloprotease:Tyrosine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the [...]
       0.827
rpm
Transcription factor TFIIS:DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
   
  
 0.746
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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