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MMP0672 MMP0672 MMP0398 MMP0398 MMP0339 MMP0339 MMP0670 MMP0670 ilvC ilvC ipa-20r ipa-20r MMP1282 MMP1282 MMP1122 MMP1122 MMP1306 MMP1306 serA serA MMP1233 MMP1233
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MMP06722-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)    
Predicted Functional Partners:
MMP0398
Conserved hypothetical archaeal protein.
  
 
 0.949
MMP0339
NUDIX hydrolase; Citation: J. Bio. Chem. (1998) 273: 20924-20928.
    0.674
MMP0670
Conserved hypothetical protein.
  
    0.548
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
     
 0.546
ipa-20r
Conserved hypothetical protein.
       0.538
MMP1282
Conseved hypothetical protein NTP-binding; Belongs to the UPF0200 family.
   
  
 0.538
MMP1122
GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain.
 
    0.520
MMP1306
Conserved hypothetical protein.
     
 0.499
serA
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.498
MMP1233
TonB-dependent receptor protein:Formate dehydrogenase, subunit FdhD.
  
    0.475
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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