STRINGSTRING
nifH nifH nifD nifD nifK nifK nifE nifE nifN nifN NifI1 NifI1 nifX nifX glnA glnA nifI2 nifI2 hcp hcp nifH-2 nifH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifHNitrogenase iron protein (nitrogenase component II); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. (275 aa)    
Predicted Functional Partners:
nifD
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
 0.999
nifK
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
 
 0.999
nifE
Nitrogenase iron-molybdenum cofactor biosynthesis protein; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family.
 
 0.999
nifN
Iron-molybdenum cofactor biosynthesis protein, subunit N; Citation: Kessler et al. 1998 J Bacteriol 180:1504-1511.
 
 
 0.999
NifI1
Nitrogen regulatory protein NifI1; Could be involved in the regulation of nitrogen fixation.
  
  
 0.998
nifX
Nitrogen fixation-related protein; Citation: Kessler et al. 1998 J Bacteriol 180:1504-1511; Gosink et al. 1990 J.Bacteriol 172:1441-1447.
 
  
 0.990
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.975
nifI2
Nitrogen regulatory protein NifI2; Could be involved in the regulation of nitrogen fixation.
  
  
 0.926
hcp
Prismane; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
 
 0.911
nifH-2
NifH/frxC family:ATP/GTP-binding site motif A (P-loop); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 
0.905
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.