node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LigT | bioF | MMP0612 | MMP1574 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 8-amino-7-oxononanoate synthase. | 0.623 |
LigT | hel308 | MMP0612 | MMP0890 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. | 0.828 |
LigT | tbp | MMP0612 | MMP0257 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | TATA-binding protein (TBP); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.724 |
MMP0457 | MMP1148 | MMP0457 | MMP1148 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Small nuclear ribonucleoprotein (Sm protein). | 0.946 |
MMP0457 | aEF-2 | MMP0457 | MMP1369 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | 0.963 |
MMP0457 | hel308 | MMP0457 | MMP0890 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. | 0.935 |
MMP0457 | ppiB | MMP0457 | MMP1128 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Peptidyl-prolyl cis-trans isomerase, cyclophilin type. | 0.946 |
MMP0457 | ppiB-2 | MMP0457 | MMP1129 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Peptidyl-prolyl cis-trans isomerase, cyclophilin type. | 0.946 |
MMP0457 | rpl7ae | MMP0457 | MMP0641 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | 0.922 |
MMP0457 | tbp | MMP0457 | MMP0257 | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | TATA-binding protein (TBP); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.793 |
MMP1148 | MMP0457 | MMP1148 | MMP0457 | Small nuclear ribonucleoprotein (Sm protein). | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | 0.946 |
MMP1148 | aEF-2 | MMP1148 | MMP1369 | Small nuclear ribonucleoprotein (Sm protein). | Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | 0.990 |
MMP1148 | flpA-2 | MMP1148 | MMP0597 | Small nuclear ribonucleoprotein (Sm protein). | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.942 |
MMP1148 | hel308 | MMP1148 | MMP0890 | Small nuclear ribonucleoprotein (Sm protein). | Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. | 0.979 |
MMP1148 | ppiB | MMP1148 | MMP1128 | Small nuclear ribonucleoprotein (Sm protein). | Peptidyl-prolyl cis-trans isomerase, cyclophilin type. | 0.941 |
MMP1148 | ppiB-2 | MMP1148 | MMP1129 | Small nuclear ribonucleoprotein (Sm protein). | Peptidyl-prolyl cis-trans isomerase, cyclophilin type. | 0.943 |
MMP1148 | rpl7ae | MMP1148 | MMP0641 | Small nuclear ribonucleoprotein (Sm protein). | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | 0.974 |
aEF-2 | MMP0457 | MMP1369 | MMP0457 | Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | Probable ATP dependent RNA helicase; Citation: Mol. Cell 2001; 8:251-62. Nucleic Acids Res. 1999; 27:3811-20. Prog. Nucleic Acid Res. Biol. 2002; 72:307-31, PNAS (2001) 98:; Belongs to the DEAD box helicase family. | 0.963 |
aEF-2 | MMP1148 | MMP1369 | MMP1148 | Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | Small nuclear ribonucleoprotein (Sm protein). | 0.990 |
aEF-2 | flpA-2 | MMP1369 | MMP0597 | Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.965 |