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aIF-5A aIF-5A rpl21e rpl21e dys dys rplA rplA rps24e rps24e rps2 rps2 rps3ae rps3ae rps6e rps6e rpsM rpsM rps4 rps4 rpl13 rpl13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aIF-5ATranslation initiation factor IF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (131 aa)    
Predicted Functional Partners:
rpl21e
Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 
 0.999
dys
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
  
 0.999
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
 0.999
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
   
   0.999
rps2
SSU Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.999
rps3ae
SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.999
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.999
rpsM
SSU ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.999
rps4
SSU ribosomal protein S4P (S9E); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.999
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.999
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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