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prf1 prf1 MMP0382 MMP0382 aEF-1 aEF-1 rpl15 rpl15 rps2 rps2 rpl10 rpl10 rplX rplX rps3ae rps3ae rpoB2 rpoB2 rps4e rps4e rpoB1 rpoB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
prf1Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (419 aa)    
Predicted Functional Partners:
MMP0382
RNase L inhibitor; Citation: J Bio Chem 270:13308-13317 1995.
  
 
 0.993
aEF-1
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.981
rpl15
LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.969
rps2
SSU Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 0.958
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.956
rplX
LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
  0.955
rps3ae
SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.951
rpoB2
DNA-directed RNA polymerase subunit B; Belongs to the RNA polymerase beta chain family.
  
 
 0.950
rps4e
SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.949
rpoB1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.945
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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