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cobQ cobQ chiB chiB cbiH cbiH hisC hisC cbiA-2 cbiA-2 cbiC cbiC cbiA cbiA cobS cobS MMP0198 MMP0198 cbiL cbiL cbiF cbiF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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cobQCobyrinic acid a,c-diamide synthase:Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (492 aa)    
Predicted Functional Partners:
chiB
Cobalamin biosynthesis protein B; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.995
cbiH
precorrin-3B C17-methyltransferase; Citation: J. Bacteriol. 175:3303-3316(1993).
  
 0.976
hisC
Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9.
 
  
 0.973
cbiA-2
Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA.
  
 0.968
cbiC
Precorrin-8X methylmutase CbiC/CobH.
  
 0.954
cbiA
Cobyrinic acid a,c-diamide synthase.
  
 0.918
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.905
MMP0198
ABC-type iron(III) transport system, ATP binding protein.
    
 0.898
cbiL
Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.845
cbiF
Precorrin-4 C11-methyltransferase; Citation: Eur J Biochem 1998 Jun 1; 254(2):341-6.
  
  
 0.836
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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