node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMP0053 | pstB | MMP0053 | MMP1098 | Protein of unknown function DUF34. | Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.873 |
MMP0053 | thyA-2 | MMP0053 | MMP1379 | Protein of unknown function DUF34. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.776 |
MMP0053 | tmk | MMP0053 | MMP1034 | Protein of unknown function DUF34. | Thymidylate kinase. | 0.431 |
MMP1126 | RNase | MMP1126 | MMP1374 | Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.639 |
MMP1126 | pcnA | MMP1126 | MMP1711 | Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.798 |
MMP1126 | thyA-2 | MMP1126 | MMP1379 | Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.731 |
RNase | MMP1126 | MMP1374 | MMP1126 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.639 |
RNase | pcnA | MMP1374 | MMP1711 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.987 |
RNase | thyA-2 | MMP1374 | MMP1379 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.851 |
RNase | tmk | MMP1374 | MMP1034 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Thymidylate kinase. | 0.584 |
dapA | thyA-2 | MMP0576 | MMP1379 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.918 |
dcd | dut | MMP1426 | MMP1075 | Bifunctional dCTP deaminase/dUTP diphosphatase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003. | 0.904 |
dcd | surE | MMP1426 | MMP1051 | Bifunctional dCTP deaminase/dUTP diphosphatase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
dcd | thyA-2 | MMP1426 | MMP1379 | Bifunctional dCTP deaminase/dUTP diphosphatase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.931 |
dcd | tmk | MMP1426 | MMP1034 | Bifunctional dCTP deaminase/dUTP diphosphatase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Thymidylate kinase. | 0.932 |
dut | dcd | MMP1075 | MMP1426 | dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003. | Bifunctional dCTP deaminase/dUTP diphosphatase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.904 |
dut | surE | MMP1075 | MMP1051 | dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.920 |
dut | thyA-2 | MMP1075 | MMP1379 | dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.931 |
dut | tmk | MMP1075 | MMP1034 | dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003. | Thymidylate kinase. | 0.934 |
pcnA | MMP1126 | MMP1711 | MMP1126 | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.798 |