STRINGSTRING
smc1 smc1 MMP1516 MMP1516 MMP1395 MMP1395 topA topA MMP0638 MMP0638 ffh ffh MMP0287 MMP0287 dapE dapE radB radB MMP1399 MMP1399 ftsY ftsY
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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smc1Structural maintenance of chromosome protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1189 aa)    
Predicted Functional Partners:
MMP1516
Conserved hypothetical archaeal protein; Citation: Mol. Microbiol. (2002) 45: 59-71.
 
 
 0.994
MMP1395
Helix-hairpin-helix motif:DEAD/DEAH box helicase:Helicase, C-terminal:Helix-hairpin-helix DNA-binding, class 1:ERCC4 domain.
 
 
 0.914
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.853
MMP0638
Conserved hypothetical protein.
   
 
 0.825
ffh
Signal recognition particle protein SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
 0.798
MMP0287
Conserved Hypothetical protein with 2 CBS domains.
 
 
 0.772
dapE
Succinyl-diaminopimelate desuccinylase.
  
 
 0.752
radB
DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity).
 
 
 0.700
MMP1399
Aspartate/glutamate/uridylate kinase.
  
    0.685
ftsY
Signal recognition particle receptor SRalpha; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
 0.670
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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