STRINGSTRING
dacZ dacZ glmM glmM manB manB leuC-2 leuC-2 cbiA cbiA cbiA-2 cbiA-2 pheT pheT MMP1611 MMP1611 dph5 dph5 MMP0285 MMP0285 agcS agcS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
dacZProtein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (312 aa)    
Predicted Functional Partners:
glmM
Phosphoglucomutase/phosphomannomutase:Calcium- binding EF-hand; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1- phosphate to glucose-6-phosphate, but at a 5-fold lower rate.
   
 
 0.882
manB
Phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family.
   
 
 0.882
leuC-2
Aconitase Family; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.864
cbiA
Cobyrinic acid a,c-diamide synthase.
  
    0.779
cbiA-2
Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA.
  
    0.778
pheT
Phenylalanyl-tRNA synthetase beta subunit.
  
  
 0.749
MMP1611
Conserved hypothetical protein.
  
   
 0.735
dph5
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
   
  
 0.721
MMP0285
Phosphoesterase, RecJ-like:TrkA-N:Phosphoesterase, DHHA1.
 
   
 0.687
agcS
Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake.
  
  
 0.681
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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