node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LigT | bioB-2 | MMP0612 | MMP1238 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | TonB-dependent receptor protein:Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.448 |
LigT | bioD | MMP0612 | MMP1573 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.692 |
LigT | bioF | MMP0612 | MMP1574 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 8-amino-7-oxononanoate synthase. | 0.623 |
MMP0017 | MMP0865 | MMP0017 | MMP0865 | Conserved hypothetical protein. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.749 |
MMP0017 | bioD | MMP0017 | MMP1573 | Conserved hypothetical protein. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.818 |
MMP0017 | bioF | MMP0017 | MMP1574 | Conserved hypothetical protein. | 8-amino-7-oxononanoate synthase. | 0.705 |
MMP0017 | bioW | MMP0017 | MMP1575 | Conserved hypothetical protein. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.717 |
MMP0865 | MMP0017 | MMP0865 | MMP0017 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein. | 0.749 |
MMP0865 | bioB | MMP0865 | MMP0126 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthetase. | 0.810 |
MMP0865 | bioB-2 | MMP0865 | MMP1238 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | TonB-dependent receptor protein:Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.986 |
MMP0865 | bioD | MMP0865 | MMP1573 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
MMP0865 | bioF | MMP0865 | MMP1574 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase. | 0.996 |
MMP0865 | bioW | MMP0865 | MMP1575 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. | 0.878 |
MMP0865 | birA | MMP0865 | MMP0119 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin--protein ligase; Citation: Mukhopadhyay et al., JBC273:5155 (1998). | 0.721 |
MMP1520 | bioD | MMP1520 | MMP1573 | Hydrogenase nickel incorporation protein HypB; ATP/GTP-binding site motif A (P-loop):HypB/UreG, nucleotide-binding:Hydrogenase accessory protein HypB. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.867 |
MMP1520 | nifH-2 | MMP1520 | MMP0147 | Hydrogenase nickel incorporation protein HypB; ATP/GTP-binding site motif A (P-loop):HypB/UreG, nucleotide-binding:Hydrogenase accessory protein HypB. | NifH/frxC family:ATP/GTP-binding site motif A (P-loop); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.657 |
bioB | MMP0865 | MMP0126 | MMP0865 | Biotin synthetase. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.810 |
bioB | bioB-2 | MMP0126 | MMP1238 | Biotin synthetase. | TonB-dependent receptor protein:Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.928 |
bioB | bioD | MMP0126 | MMP1573 | Biotin synthetase. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.991 |
bioB | bioF | MMP0126 | MMP1574 | Biotin synthetase. | 8-amino-7-oxononanoate synthase. | 0.710 |