STRINGSTRING
ssh10b_1 ssh10b_1 cofG cofG MMP1612 MMP1612 MMP0091 MMP0091 MMP0914 MMP0914 mcrA mcrA adkA adkA MMP1188 MMP1188 MMP1611 MMP1611 dnaG dnaG rpl39e rpl39e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
ssh10b_1Protein of unknown function DUF78; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (89 aa)    
Predicted Functional Partners:
cofG
FO synthase, subunit CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
      
 0.748
MMP1612
Conserved hypothetical protein.
 
     0.693
MMP0091
Conserved hypothetical archaeal protein.
  
    0.689
MMP0914
Conserved hypothetical archaeal protein.
  
    0.687
mcrA
Methyl-coenzyme M reductase I, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
  
 0.664
adkA
Adenylate kinase; Ferber DM, Haney PJ, Berk H, Lynn D, Konisky J. (1997) Gene 185:239-44; Citation: Rusnak P, Haney P, Konisky J. (1995) J Bacteriol 177:2977-81.
  
     0.640
MMP1188
Conserved hypothetical archaeal protein; Belongs to the UPF0147 family.
  
     0.632
MMP1611
Conserved hypothetical protein.
 
     0.609
dnaG
Possible DnaG-type primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.591
rpl39e
LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family.
  
     0.573
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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