STRINGSTRING
ABK72925.1 ABK72925.1 gyrA gyrA ABK76200.1 ABK76200.1 ABK74439.1 ABK74439.1 ABK72739.1 ABK72739.1 ABK74160.1 ABK74160.1 ABK70092.1 ABK70092.1 ABK73217.1 ABK73217.1 ABK70066.1 ABK70066.1 ABK70495.1 ABK70495.1 gyrB gyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK72925.1Conserved hypothetical protein. (260 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.891
ABK76200.1
Bacterial type II secretion system protein F domain; Identified by match to protein family HMM PF00482.
  
   
 0.762
ABK74439.1
Conserved hypothetical protein.
  
     0.718
ABK72739.1
FAD-binding 9, siderophore-interacting; Identified by match to protein family HMM PF04954; match to protein family HMM PF08021.
  
  
 0.713
ABK74160.1
Conserved hypothetical protein.
  
    0.713
ABK70092.1
Ferric enterobactin transport system permease protein FepD; Identified by match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
  
 0.708
ABK73217.1
Conserved hypothetical protein.
 
    0.701
ABK70066.1
Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM TIGR01409.
  
    0.645
ABK70495.1
Conserved hypothetical protein.
  
    0.644
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.624
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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