STRINGSTRING
ABK73862.1 ABK73862.1 ABK76080.1 ABK76080.1 ABK73869.1 ABK73869.1 eccB1 eccB1 ABK72665.1 ABK72665.1 ABK74495.1 ABK74495.1 eccCb1 eccCb1 esxB esxB eccA1 eccA1 espE espE esxA esxA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK73862.1Conserved hypothetical protein. (462 aa)    
Predicted Functional Partners:
ABK76080.1
Probable conserved transmembrane protein; Identified by match to protein family HMM PF04600; match to protein family HMM TIGR02958.
 
  
 0.681
ABK73869.1
Nitrate/nitrite response regulator protein; Identified by match to protein family HMM PF00072.
  
 
 0.624
eccB1
Conserved hypothetical protein; An ATPase (shown for residues 72-479). Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains ; Belongs to the EccB family.
 
  
 0.571
ABK72665.1
RNA polymerase sigma-F factor; Identified by match to protein family HMM PF04539; match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; match to protein family HMM TIGR02980; Belongs to the sigma-70 factor family.
 
  
 0.563
ABK74495.1
Identified by match to protein family HMM PF01580.
 
  
 0.550
eccCb1
Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains.
 
  
 0.542
esxB
Conserved hypothetical protein; An exported protein. Plays a role in DNA conjugation, in at least a donor strain ; Belongs to the WXG100 family. CFP-10 subfamily.
  
 
 0.487
eccA1
ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity).
 
  
 0.483
espE
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.474
esxA
Early secretory antigenic target, 6 kDa; An exported protein. Unlike its M.tuberculosis counterpart has poor pore forming ability in artificial liposomes, does not undergo conformational change at acidic pH. Mutation of 2 residues to those found in M.tuberculosis (25-TA-26 to IH) alters the properties of this protein so that it inserts into liposomes at acidic pH, forming pores, like its M.tuberculosis counterpart.
  
 
 0.452
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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