STRINGSTRING
ABK74495.1 ABK74495.1 eccCb1 eccCb1 eccB1 eccB1 ABK72095.1 ABK72095.1 eccA1 eccA1 ABK76080.1 ABK76080.1 espG1 espG1 eccE1 eccE1 espE espE ABK73967.1 ABK73967.1 mycP1 mycP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK74495.1Identified by match to protein family HMM PF01580. (742 aa)    
Predicted Functional Partners:
eccCb1
Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains.
   
0.990
eccB1
Conserved hypothetical protein; An ATPase (shown for residues 72-479). Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains ; Belongs to the EccB family.
 
 
 0.980
ABK72095.1
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.944
eccA1
ATPase, AAA family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains. EccA1 exhibits ATPase activity and may provide energy for the export of ESX-1 substrates (By similarity).
 
  
 0.919
ABK76080.1
Probable conserved transmembrane protein; Identified by match to protein family HMM PF04600; match to protein family HMM TIGR02958.
 
  
 0.902
espG1
Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Specific chaperone for cognate PE/PPE proteins, plays an important role in preventing aggregation of PE/PPE dimers (By similarity). Also plays a role in DNA conjugation, in at least recipient strain (By similarity). ECO:0000250|UniProtKB:L8FPI5, ; Belongs to the EspG family.
  
  
 0.886
eccE1
Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in at least a donor strain.
 
 
 0.875
espE
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.846
ABK73967.1
Probable conserved membrane protein; Identified by match to protein family HMM PF05108.
 
 
 0.842
mycP1
Membrane-anchored mycosin mycp1; May play a dual role in regulation of ESX-1 secretion and virulence. Acts as a protease that cleaves EspB. Belongs to the peptidase S8 family.
 
 
 0.823
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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