STRINGSTRING
ABK73135.1 ABK73135.1 thiD thiD ABK72576.1 ABK72576.1 ABK74118.1 ABK74118.1 ABK71348.1 ABK71348.1 thiG thiG thiC thiC thiE thiE ABK74591.1 ABK74591.1 purM purM ABK69733.1 ABK69733.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
ABK73135.1Identified by match to protein family HMM PF01964. (475 aa)    
Predicted Functional Partners:
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
 
 
 0.976
ABK72576.1
NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
  
  
 0.957
ABK74118.1
PntAB protein.
  
  
 0.957
ABK71348.1
Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
  
  
 0.957
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.924
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 
0.902
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.851
ABK74591.1
oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
  
  
 0.829
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878.
  
 
 0.821
ABK69733.1
NAD-dependent formate dehydrogenase delta subunit.
   
  
 0.819
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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