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ABK71348.1 ABK71348.1 pntB pntB ABK72576.1 ABK72576.1 ABK74118.1 ABK74118.1 pntB-2 pntB-2 ABK73135.1 ABK73135.1 sthA sthA nadK nadK sir2 sir2 pntA-2 pntA-2 nadE nadE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK71348.1Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222. (360 aa)    
Predicted Functional Partners:
pntB
NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
ABK72576.1
NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
ABK74118.1
PntAB protein.
 
 
 0.999
pntB-2
NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
ABK73135.1
Identified by match to protein family HMM PF01964.
  
  
 0.957
sthA
Soluble pyridine nucleotide transhydrogenase; Identified by similarity to SP:P27306; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 
 0.915
nadK
Inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.910
sir2
NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
    
 0.909
pntA-2
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
  
  
 
0.908
nadE
Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.908
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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