node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70417.1 | ABK74387.1 | MSMEG_0215 | MSMEG_0211 | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.754 |
ABK70417.1 | ABK75155.1 | MSMEG_0215 | MSMEG_0213 | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | Transcriptional regulator; Identified by match to protein family HMM PF00165. | 0.754 |
ABK70417.1 | ABK75158.1 | MSMEG_0215 | MSMEG_0212 | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | Lyase; Identified by match to protein family HMM PF00903. | 0.757 |
ABK70417.1 | ABK75388.1 | MSMEG_0215 | MSMEG_0214 | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | L-sorbosone dehydrogenase. | 0.887 |
ABK71856.1 | ABK74387.1 | MSMEG_1952 | MSMEG_0211 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.616 |
ABK71856.1 | pcrA | MSMEG_1952 | MSMEG_5534 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073. | 0.966 |
ABK71856.1 | recA | MSMEG_1952 | MSMEG_2723 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.987 |
ABK71856.1 | uvrB | MSMEG_1952 | MSMEG_3816 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.850 |
ABK71856.1 | uvrC | MSMEG_1952 | MSMEG_3078 | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.634 |
ABK74387.1 | ABK70417.1 | MSMEG_0211 | MSMEG_0215 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | 0.754 |
ABK74387.1 | ABK71856.1 | MSMEG_0211 | MSMEG_1952 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580. | 0.616 |
ABK74387.1 | ABK75155.1 | MSMEG_0211 | MSMEG_0213 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Transcriptional regulator; Identified by match to protein family HMM PF00165. | 0.802 |
ABK74387.1 | ABK75158.1 | MSMEG_0211 | MSMEG_0212 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Lyase; Identified by match to protein family HMM PF00903. | 0.840 |
ABK74387.1 | ABK75388.1 | MSMEG_0211 | MSMEG_0214 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | L-sorbosone dehydrogenase. | 0.756 |
ABK74387.1 | mfd | MSMEG_0211 | MSMEG_5423 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.788 |
ABK74387.1 | pcrA | MSMEG_0211 | MSMEG_5534 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073. | 0.656 |
ABK74387.1 | recA | MSMEG_0211 | MSMEG_2723 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.637 |
ABK74387.1 | uvrB | MSMEG_0211 | MSMEG_3816 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.978 |
ABK74387.1 | uvrC | MSMEG_0211 | MSMEG_3078 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.719 |
ABK75155.1 | ABK70417.1 | MSMEG_0213 | MSMEG_0215 | Transcriptional regulator; Identified by match to protein family HMM PF00165. | Identified by match to protein family HMM PF02678; Belongs to the pirin family. | 0.754 |