node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70326.1 | ABK73330.1 | MSMEG_4863 | MSMEG_2896 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.480 |
ABK70326.1 | ABK73410.1 | MSMEG_4863 | MSMEG_0341 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.718 |
ABK70326.1 | ABK74368.1 | MSMEG_4863 | MSMEG_1497 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | acyl-CoA dehydrogenase family protein member 8; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028. | 0.773 |
ABK71916.1 | ABK72268.1 | MSMEG_5998 | MSMEG_6703 | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | 0.707 |
ABK71916.1 | ABK73410.1 | MSMEG_5998 | MSMEG_0341 | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.647 |
ABK71916.1 | cofD | MSMEG_5998 | MSMEG_1830 | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.930 |
ABK71916.1 | fbiB | MSMEG_5998 | MSMEG_1829 | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...] | 0.911 |
ABK71916.1 | fbiD | MSMEG_5998 | MSMEG_2392 | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.772 |
ABK72268.1 | ABK71916.1 | MSMEG_6703 | MSMEG_5998 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | 0.707 |
ABK72268.1 | ABK73410.1 | MSMEG_6703 | MSMEG_0341 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.560 |
ABK72268.1 | ABK75334.1 | MSMEG_6703 | MSMEG_2027 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | 0.577 |
ABK72268.1 | cofD | MSMEG_6703 | MSMEG_1830 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.727 |
ABK72268.1 | fbiB | MSMEG_6703 | MSMEG_1829 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...] | 0.716 |
ABK72268.1 | fbiD | MSMEG_6703 | MSMEG_2392 | N5,N10- methylenetetrahydromethanopterin reductase-related protein. | Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.591 |
ABK73330.1 | ABK70326.1 | MSMEG_2896 | MSMEG_4863 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.480 |
ABK73330.1 | ABK73410.1 | MSMEG_2896 | MSMEG_0341 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.571 |
ABK73330.1 | cofD | MSMEG_2896 | MSMEG_1830 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.508 |
ABK73330.1 | fbiB | MSMEG_2896 | MSMEG_1829 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...] | 0.419 |
ABK73410.1 | ABK70326.1 | MSMEG_0341 | MSMEG_4863 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | 0.718 |
ABK73410.1 | ABK71916.1 | MSMEG_0341 | MSMEG_5998 | Conserved hypothetical protein; Identified by match to protein family HMM PF00296. | Conserved hypothetical protein; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. | 0.647 |