STRINGSTRING
tylF tylF gtf1 gtf1 ABK75432.1 ABK75432.1 ABK71734.1 ABK71734.1 pks pks ABK72522.1 ABK72522.1 ABK70957.1 ABK70957.1 ABK71204.1 ABK71204.1 ABK71245.1 ABK71245.1 stf0 stf0 ABK71089.1 ABK71089.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tylFMacrocin-O-methyltransferase; Identified by match to protein family HMM PF05711. (240 aa)    
Predicted Functional Partners:
gtf1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
  
 0.790
ABK75432.1
Putative acyltransferase; Identified by match to protein family HMM PF01757.
 
  
 0.678
ABK71734.1
Rmt2 protein.
 
    0.651
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
 
 
 0.585
ABK72522.1
NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.
 
 
 0.535
ABK70957.1
Conserved hypothetical protein.
 
  
 0.535
ABK71204.1
Rmt3 protein.
 
   
0.498
ABK71245.1
O-acyl transferase; Identified by match to protein family HMM PF01757.
 
   
 0.492
stf0
Conserved hypothetical protein; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid in pathogenic mycobacteria. Cannot use free glucose and unnatural stereoisomers of trehalose (alpha,beta (neo-trehalose) and beta,beta (iso-trehalose)) as substrates.
 
     0.474
ABK71089.1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
   
 0.460
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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