STRINGSTRING
gap-2 gap-2 mps2 mps2 ABK75036.1 ABK75036.1 ABK74005.1 ABK74005.1 mbtH mbtH sap sap ecf ecf stf0 stf0
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
gap-2Integral membrane protein; Required for the transport of peptidoglycolipids (GPLs) to the cell surface. (272 aa)    
Predicted Functional Partners:
mps2
Linear gramicidin synthetase subunit D; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; match to protein family HMM TIGR01746.
  
    0.745
ABK75036.1
Putative non-ribosomal peptide synthase; Identified by match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720.
  
    0.733
ABK74005.1
Peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family.
  
    0.732
mbtH
Conserved domain protein; Identified by match to protein family HMM PF03621.
  
    0.646
sap
Sigma associated protein; Identified by match to protein family HMM PF04946.
  
    0.533
ecf
Extra cytoplasmic sigma factor; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family.
  
    0.528
stf0
Conserved hypothetical protein; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid in pathogenic mycobacteria. Cannot use free glucose and unnatural stereoisomers of trehalose (alpha,beta (neo-trehalose) and beta,beta (iso-trehalose)) as substrates.
      
 0.430
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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