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ABK72641.1 ABK72641.1 ABK70153.1 ABK70153.1 ABK69831.1 ABK69831.1 rpoB rpoB rpoC rpoC whiB whiB rshA rshA ABK75430.1 ABK75430.1 ABK75721.1 ABK75721.1 ABK74866.1 ABK74866.1 rpoA rpoA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ABK72641.1Putative ECF sigma factor RpoE1; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (217 aa)    
Predicted Functional Partners:
ABK70153.1
Transcriptional regulator, AraC family protein.
  
  
 0.833
ABK69831.1
Starvation-inducible DNA-binding protein or fine tangled pili major subunit; Identified by match to protein family HMM PF00210; Belongs to the Dps family.
   
  
 0.789
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
  
 
 0.715
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.715
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
  
 0.659
rshA
Anti-sigma factor, family protein; A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable). Overexpression leads to increased susceptibility to diamide.
  
 
 0.575
ABK75430.1
Dihydrofolate reductase.
  
  
 0.531
ABK75721.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
 
  
0.527
ABK74866.1
Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family.
 
  
 0.516
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.509
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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