STRINGSTRING
thiS thiS thiG thiG thiO thiO thiE thiE ABK69677.1 ABK69677.1 ABK71634.1 ABK71634.1 ABK73517.1 ABK73517.1 ABK75055.1 ABK75055.1 ABK73379.1 ABK73379.1 tilS tilS FbiC FbiC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
thiSThiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. (66 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.999
thiO
Glycine oxidase ThiO; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352.
 
  
 0.966
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.943
ABK69677.1
Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.
  
 
 0.916
ABK71634.1
Identified by match to protein family HMM PF00899.
  
 
 0.882
ABK73517.1
Identified by match to protein family HMM PF01398.
  
 
 0.821
ABK75055.1
ABC transporter integral membrane subunit.
 
    0.792
ABK73379.1
Conserved hypothetical protein.
  
    0.785
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.784
FbiC
FO synthase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00423.
  
  
 0.754
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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