STRINGSTRING
ABK73379.1 ABK73379.1 thiG thiG thiO thiO thiS thiS ABK74364.1 ABK74364.1 ABK75055.1 ABK75055.1 thiE thiE ABK75637.1 ABK75637.1 ABK75770.1 ABK75770.1 ABK69692.1 ABK69692.1 ABK75269.1 ABK75269.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK73379.1Conserved hypothetical protein. (249 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
    0.786
thiO
Glycine oxidase ThiO; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352.
  
    0.785
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
    0.785
ABK74364.1
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005.
  
  
 0.773
ABK75055.1
ABC transporter integral membrane subunit.
  
  
 0.769
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
    0.621
ABK75637.1
Transcriptional regulator; Identified by match to protein family HMM PF00196; match to protein family HMM PF07721.
  
    0.575
ABK75770.1
Identified by match to protein family HMM PF01341; Belongs to the glycosyl hydrolase family 6.
 
 
 0.570
ABK69692.1
Transcriptional regulatory protein; Identified by match to protein family HMM PF00196.
  
     0.548
ABK75269.1
Conserved hypothetical protein; Identified by match to protein family HMM PF01987.
  
     0.539
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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