STRINGSTRING
ABK69605.1 ABK69605.1 ABK69772.1 ABK69772.1 ABK74575.1 ABK74575.1 rpoB rpoB ABK74117.1 ABK74117.1 rpoZ rpoZ rpoA rpoA atpE atpE ABK75667.1 ABK75667.1 ABK73456.1 ABK73456.1 ABK70452.1 ABK70452.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK69605.1Possible chalcone synthase Pks10; Identified by match to protein family HMM PF00195; match to protein family HMM PF02797. (362 aa)    
Predicted Functional Partners:
ABK69772.1
Isoprenylcysteine carboxyl methyltransferase; Identified by match to protein family HMM PF04140.
 
  
 0.997
ABK74575.1
Oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494.
 
  
 0.996
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
   
 0.881
ABK74117.1
Conserved hypothetical protein.
  
 0.858
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.835
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.818
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.805
ABK75667.1
Identified by match to protein family HMM PF00581; match to protein family HMM PF00753.
    
 
 0.757
ABK73456.1
Amine oxidase [flavin-containing] B; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593.
   
 
 0.753
ABK70452.1
SNF2 domain protein; Identified by match to protein family HMM PF00176.
  
 0.724
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (20%) [HD]