STRINGSTRING
ABK73210.1 ABK73210.1 psd psd ABK75709.1 ABK75709.1 ABK70814.1 ABK70814.1 prcB prcB ABK71448.1 ABK71448.1 prcA prcA ABK71825.1 ABK71825.1 mpa mpa ABK72388.1 ABK72388.1 ABK74628.1 ABK74628.1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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textmining
co-expression
protein homology
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ABK73210.1Cell division control protein Cdc48; Identified by match to protein family HMM PF00004; match to protein family HMM PF02359; Belongs to the AAA ATPase family. (745 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
  
 0.931
ABK75709.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
    0.912
ABK70814.1
Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
  
 0.853
prcB
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.smegmatis proteasome is able to cleave oligopeptides after hydrophobic residues, thus displaying chymotrypsin-like activity. In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin- like protein (Pup). Among the identified substrates of the M.smegmatis proteasome are the pupylated SodA and Ino1 proteins. The Pup-proteasome system (PPS) is essential for survival under starvation; PPS likely functions to r [...]
 
 0.803
ABK71448.1
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 0.803
prcA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The M.smegmatis proteasome is able to cleave oligopeptides after hydrophobic residues, thus displaying chymotrypsin-like activity. In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin- like protein (Pup). Identified substrates of the M.smegmatis proteasome are the pupylated SodA and Ino1 proteins. The Pup- proteasome system (PPS) is essential for survival under starvation; PPS likely functions to recycle a [...]
  
 0.771
ABK71825.1
Short chain dehydrogenase; Identified by match to protein family HMM PF00106.
  
 0.768
mpa
ATPase, AAA family protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
0.761
ABK72388.1
Hypothetical ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00970; match to protein family HMM PF04954; match to protein family HMM PF08021.
 
 0.760
ABK74628.1
Histone deacetylase superfamily protein; Identified by match to protein family HMM PF00850.
  
 0.744
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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