STRINGSTRING
hemB hemB hemC hemC hemD hemD hemL hemL ABK70203.1 ABK70203.1 ABK70619.1 ABK70619.1 hemA hemA cobA cobA hemE hemE ABK74808.1 ABK74808.1 ABK74496.1 ABK74496.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hemBDelta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (326 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
hemD
uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602.
 
 
 0.998
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM TIGR00713.
 
 
 0.993
ABK70203.1
Glutamate-1-semialdehyde 2,1-aminomutase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.990
ABK70619.1
Probable glutamate-1-semialdehyde 2,1-aminomutase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.987
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.986
cobA
uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470.
 
  
 0.926
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.895
ABK74808.1
Putative transmembrane protein.
  
    0.862
ABK74496.1
uroporphyrinogen-III synthetase; Identified by match to protein family HMM PF00486; match to protein family HMM PF02602.
  
 
 0.781
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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