STRINGSTRING
nrdE1 nrdE1 ABK72117.1 ABK72117.1 nrdB nrdB ABK71415.1 ABK71415.1 ABK75047.1 ABK75047.1 ABK71958.1 ABK71958.1 ABK74759.1 ABK74759.1 ABK70667.1 ABK70667.1 cmk cmk adk adk ndk ndk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdE1Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family. (706 aa)    
Predicted Functional Partners:
ABK72117.1
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.997
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Probable oxidase that might be involved in lipid metabolism. Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
  
 0.990
ABK71415.1
Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268.
 
 
 0.979
ABK75047.1
Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.
 
 0.971
ABK71958.1
Glutaredoxin; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194.
 
 0.970
ABK74759.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.
   
 0.962
ABK70667.1
Thymidylate kinase; Identified by match to protein family HMM PF02223.
  
 
 0.941
cmk
Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.
  
 
 0.926
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.921
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.919
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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