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fni fni ispH ispH uppS-2 uppS-2 ABK70694.1 ABK70694.1 ABK75553.1 ABK75553.1 ABK70459.1 ABK70459.1 ABK73942.1 ABK73942.1 ABK72779.1 ABK72779.1 ABK75535.1 ABK75535.1 ABK70136.1 ABK70136.1 sppA sppA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (341 aa)    
Predicted Functional Partners:
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.961
uppS-2
Undecaprenyl diphosphate synthase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall.
 
  
 0.923
ABK70694.1
Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
 
 0.916
ABK75553.1
Hypothetical protein; Identified by Glimmer2; putative.
  
   
 0.869
ABK70459.1
Conserved hypothetical protein.
  
  
 0.802
ABK73942.1
GntR-family protein transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
  
  
 0.802
ABK72779.1
Hypothetical protein; Identified by Glimmer2; putative; Belongs to the WXG100 family.
      
 0.754
ABK75535.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family.
     
 0.753
ABK70136.1
D-lactate dehydrogenase; Identified by match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
  
 0.701
sppA
Signal peptide peptidase SppA, 67K type; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706.
     
 0.694
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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