ABK71897.1 protein (Mycolicibacterium smegmatis)

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Score

ABK71897.1

Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781. (291 aa)

Predicted Functional Partners:

egtD

0.926

ABK71307.1

0.903

ABK73930.1

0.897

ABK75130.1

0.881

egtE

0.808

egtA

0.735

ABK75797.1

0.573

dinB-2

0.561

ABK75054.1

0.507

egtB

0.499

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK71307.1	ABK71897.1	MSMEG_1286	MSMEG_1226	Identified by match to protein family HMM PF00884.	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	0.903
ABK71307.1	ABK73930.1	MSMEG_1286	MSMEG_1228	Identified by match to protein family HMM PF00884.	Sulfatase; Identified by match to protein family HMM PF00884.	0.660
ABK71307.1	ABK75130.1	MSMEG_1286	MSMEG_1451	Identified by match to protein family HMM PF00884.	Arylsulfatase; Identified by match to protein family HMM PF00884.	0.505
ABK71307.1	egtB	MSMEG_1286	MSMEG_6249	Identified by match to protein family HMM PF00884.	Conserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Cannot use the alternative thiols cysteine, N- acetylcysteine, or glutathione instead of gamma-glutamylcysteine as substrates, and histidine is a poor sulfur acceptor substrate compared to hercynine; Belongs to the EgtB family.	0.413
ABK71897.1	ABK71307.1	MSMEG_1226	MSMEG_1286	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Identified by match to protein family HMM PF00884.	0.903
ABK71897.1	ABK73930.1	MSMEG_1226	MSMEG_1228	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Sulfatase; Identified by match to protein family HMM PF00884.	0.897
ABK71897.1	ABK75054.1	MSMEG_1226	MSMEG_6339	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Identified by match to protein family HMM PF00753.	0.507
ABK71897.1	ABK75130.1	MSMEG_1226	MSMEG_1451	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Arylsulfatase; Identified by match to protein family HMM PF00884.	0.881
ABK71897.1	ABK75797.1	MSMEG_1226	MSMEG_1225	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Conserved hypothetical protein.	0.573
ABK71897.1	dinB-2	MSMEG_1226	MSMEG_2294	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	DNA polymerase IV; Identified by match to protein family HMM PF00817.	0.561
ABK71897.1	egtA	MSMEG_1226	MSMEG_6250	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC) (By similarity). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.	0.735
ABK71897.1	egtB	MSMEG_1226	MSMEG_6249	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Conserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Cannot use the alternative thiols cysteine, N- acetylcysteine, or glutathione instead of gamma-glutamylcysteine as substrates, and histidine is a poor sulfur acceptor substrate compared to hercynine; Belongs to the EgtB family.	0.499
ABK71897.1	egtD	MSMEG_1226	MSMEG_6247	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Conserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine. Among all the proteinogenic amino acids, only L-histidine is a substrate.	0.926
ABK71897.1	egtE	MSMEG_1226	MSMEG_6246	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	Pyridoxal-phosphate-dependent transferase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine. Ergothioneine is a secreted antioxidant that protects mycobacterium from oxidative stress. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.	0.808
ABK73930.1	ABK71307.1	MSMEG_1228	MSMEG_1286	Sulfatase; Identified by match to protein family HMM PF00884.	Identified by match to protein family HMM PF00884.	0.660
ABK73930.1	ABK71897.1	MSMEG_1228	MSMEG_1226	Sulfatase; Identified by match to protein family HMM PF00884.	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	0.897
ABK73930.1	egtB	MSMEG_1228	MSMEG_6249	Sulfatase; Identified by match to protein family HMM PF00884.	Conserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Cannot use the alternative thiols cysteine, N- acetylcysteine, or glutathione instead of gamma-glutamylcysteine as substrates, and histidine is a poor sulfur acceptor substrate compared to hercynine; Belongs to the EgtB family.	0.405
ABK75054.1	ABK71897.1	MSMEG_6339	MSMEG_1226	Identified by match to protein family HMM PF00753.	Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.	0.507
ABK75054.1	ABK75130.1	MSMEG_6339	MSMEG_1451	Identified by match to protein family HMM PF00753.	Arylsulfatase; Identified by match to protein family HMM PF00884.	0.674
ABK75130.1	ABK71307.1	MSMEG_1451	MSMEG_1286	Arylsulfatase; Identified by match to protein family HMM PF00884.	Identified by match to protein family HMM PF00884.	0.505