STRINGSTRING
ABK73930.1 ABK73930.1 ABK71897.1 ABK71897.1 ABK75199.1 ABK75199.1 gyrB-2 gyrB-2 ABK71307.1 ABK71307.1 rpoB rpoB ABK74775.1 ABK74775.1 glgC glgC ABK74460.1 ABK74460.1 ABK73383.1 ABK73383.1 ABK72679.1 ABK72679.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK73930.1Sulfatase; Identified by match to protein family HMM PF00884. (450 aa)    
Predicted Functional Partners:
ABK71897.1
Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.
 
   0.897
ABK75199.1
Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.
 
   0.845
gyrB-2
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.761
ABK71307.1
Identified by match to protein family HMM PF00884.
 
    0.660
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
   
 
 0.643
ABK74775.1
Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
  
    0.612
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
   
  
 0.610
ABK74460.1
Conserved hypothetical protein.
  
 
 0.603
ABK73383.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06742; match to protein family HMM PF06863.
 
     0.579
ABK72679.1
Toluate 1,2-dioxygenase electron transfer component; Identified by match to protein family HMM PF00106; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF07729; match to protein family HMM PF08021.
  
 0.575
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (22%) [HD]