STRINGSTRING
ABK74900.1 ABK74900.1 ABK75674.1 ABK75674.1 saeC saeC ABK73018.1 ABK73018.1 gmk gmk ABK70355.1 ABK70355.1 ABK70886.1 ABK70886.1 atpE atpE groS groS glyA glyA nuoC nuoC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK74900.1Conserved hypothetical protein. (312 aa)    
Predicted Functional Partners:
ABK75674.1
Conserved hypothetical protein.
  
  
 0.825
saeC
Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain.
  
 0.782
ABK73018.1
SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994.
  
 
 0.705
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.647
ABK70355.1
Hydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389.
  
 
 0.621
ABK70886.1
Leupeptin-inactivating enzyme 1; Identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389.
  
 
 0.621
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 
 0.563
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
  0.562
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.561
nuoC
NADH-quinone oxidoreductase chain c; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
  
 
  0.559
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (18%) [HD]