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ABK75006.1 ABK75006.1 ABK69927.1 ABK69927.1 ABK73714.1 ABK73714.1 ABK74153.1 ABK74153.1 dnaJ dnaJ dnaJ-2 dnaJ-2 soxR soxR glnA-2 glnA-2 ABK74955.1 ABK74955.1 glnA glnA sigA sigA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK75006.1Transcriptional regulator, MerR family protein; Identified by match to protein family HMM PF00376. (133 aa)    
Predicted Functional Partners:
ABK69927.1
Integral membrane transporter; Identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF01740.
 
    0.820
ABK73714.1
Transcriptional regulator, MerR family protein; Identified by match to protein family HMM PF00376.
  
    0.766
ABK74153.1
MerR-family protein transcriptional regulator; Identified by match to protein family HMM PF00376.
  
    0.674
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.603
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.601
soxR
Redox-sensitive transcriptional activator SoxR; Identified by similarity to SP:P22538; match to protein family HMM PF00376; match to protein family HMM TIGR01950.
  
     0.544
glnA-2
Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
 
 
 0.510
ABK74955.1
Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.457
glnA
Glutamine synthetase, catalytic domain; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
  
 
 0.454
sigA
Sigma factor MysA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.453
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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