STRINGSTRING
ABK69695.1 ABK69695.1 hisB hisB ABK71789.1 ABK71789.1 hisH hisH pheA pheA hisC hisC hisC-2 hisC-2 hisF hisF ABK75787.1 ABK75787.1 ABK75655.1 ABK75655.1 ABK71806.1 ABK71806.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK69695.1Histidinol-phosphate aminotransferase 2; Identified by match to protein family HMM PF00155. (337 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
 
 0.997
ABK71789.1
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153.
  
 
 0.966
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.946
pheA
Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842.
  
 
 0.922
hisC
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 
0.921
hisC-2
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.919
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
  
 0.915
ABK75787.1
Inositol monophosphatase; Identified by match to protein family HMM PF00459; match to protein family HMM TIGR02067.
  
 
 0.914
ABK75655.1
D-amino-acid dehydrogenase; Identified by match to protein family HMM PF01266.
  
 
 0.910
ABK71806.1
Acetolactate synthase; Identified by match to protein family HMM PF02775; match to protein family HMM PF02776.
 
  
 0.909
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.