STRINGSTRING
ABK71821.1 ABK71821.1 ABK76180.1 ABK76180.1 ABK70833.1 ABK70833.1 topoN topoN ABK71647.1 ABK71647.1 ABK74029.1 ABK74029.1 topoM topoM ABK74518.1 ABK74518.1 ABK74950.1 ABK74950.1 ABK75665.1 ABK75665.1 ABK75624.1 ABK75624.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ABK71821.1Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. (222 aa)    
Predicted Functional Partners:
ABK76180.1
Integral membrane protein; Identified by match to protein family HMM PF00892.
 
    0.814
ABK70833.1
Regulatory protein, putative; Identified by match to protein family HMM PF07905.
  
    0.770
topoN
DNA topoisomerase IV subunit B; Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase.
 
  
 0.685
ABK71647.1
Amino acid permease-associated region; Identified by match to protein family HMM PF00324.
 
    0.678
ABK74029.1
D-aminopeptidase; Identified by match to protein family HMM PF03576.
 
    0.636
topoM
DNA gyrase subunit A; Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase.
  
  
 0.617
ABK74518.1
Identified by match to protein family HMM PF07905.
  
     0.606
ABK74950.1
Conserved hypothetical protein.
  
    0.572
ABK75665.1
Integral membrane protein; Identified by match to protein family HMM PF00892.
 
  
 0.571
ABK75624.1
Helix-turn-helix, Fis-type; Identified by match to protein family HMM PF02954; match to protein family HMM PF07905.
  
    0.552
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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