STRINGSTRING
ABK75665.1 ABK75665.1 ABK75505.1 ABK75505.1 lfrR lfrR ABK71821.1 ABK71821.1 ABK70833.1 ABK70833.1 ABK74090.1 ABK74090.1 nnrD nnrD ABK74910.1 ABK74910.1 topoN topoN ABK75465.1 ABK75465.1 ABK71623.1 ABK71623.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK75665.1Integral membrane protein; Identified by match to protein family HMM PF00892. (327 aa)    
Predicted Functional Partners:
ABK75505.1
Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00155; match to protein family HMM PF00392.
 
  
 0.703
lfrR
TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene.
 
  
 0.596
ABK71821.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
 
  
 0.571
ABK70833.1
Regulatory protein, putative; Identified by match to protein family HMM PF07905.
  
    0.531
ABK74090.1
Integral membrane protein.
 
 
 0.513
nnrD
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
  
  
 0.499
ABK74910.1
Conserved hypothetical protein; Identified by match to protein family HMM PF07336.
 
  
 0.479
topoN
DNA topoisomerase IV subunit B; Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase.
 
    0.440
ABK75465.1
Transcriptional regulator; Identified by match to protein family HMM PF00196.
 
  
 0.435
ABK71623.1
Integral membrane protein.
 
 
 0.426
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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