node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70833.1 | ABK71821.1 | MSMEG_3975 | MSMEG_1506 | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | 0.770 |
ABK70833.1 | ABK75465.1 | MSMEG_3975 | MSMEG_6828 | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | Transcriptional regulator; Identified by match to protein family HMM PF00196. | 0.487 |
ABK70833.1 | ABK75665.1 | MSMEG_3975 | MSMEG_1571 | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.531 |
ABK70833.1 | lfrR | MSMEG_3975 | MSMEG_6223 | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene. | 0.403 |
ABK70833.1 | topoN | MSMEG_3975 | MSMEG_0457 | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | DNA topoisomerase IV subunit B; Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase. | 0.752 |
ABK71623.1 | ABK75665.1 | MSMEG_5407 | MSMEG_1571 | Integral membrane protein. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.426 |
ABK71821.1 | ABK70833.1 | MSMEG_1506 | MSMEG_3975 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | 0.770 |
ABK71821.1 | ABK75665.1 | MSMEG_1506 | MSMEG_1571 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.571 |
ABK71821.1 | lfrR | MSMEG_1506 | MSMEG_6223 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene. | 0.408 |
ABK71821.1 | topoN | MSMEG_1506 | MSMEG_0457 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | DNA topoisomerase IV subunit B; Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase. | 0.685 |
ABK74090.1 | ABK75665.1 | MSMEG_0720 | MSMEG_1571 | Integral membrane protein. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.513 |
ABK74910.1 | ABK75665.1 | MSMEG_4029 | MSMEG_1571 | Conserved hypothetical protein; Identified by match to protein family HMM PF07336. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.479 |
ABK75465.1 | ABK70833.1 | MSMEG_6828 | MSMEG_3975 | Transcriptional regulator; Identified by match to protein family HMM PF00196. | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | 0.487 |
ABK75465.1 | ABK75665.1 | MSMEG_6828 | MSMEG_1571 | Transcriptional regulator; Identified by match to protein family HMM PF00196. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.435 |
ABK75465.1 | lfrR | MSMEG_6828 | MSMEG_6223 | Transcriptional regulator; Identified by match to protein family HMM PF00196. | TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene. | 0.630 |
ABK75505.1 | ABK75665.1 | MSMEG_1572 | MSMEG_1571 | Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00155; match to protein family HMM PF00392. | Integral membrane protein; Identified by match to protein family HMM PF00892. | 0.703 |
ABK75505.1 | nnrD | MSMEG_1572 | MSMEG_1573 | Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00155; match to protein family HMM PF00392. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...] | 0.571 |
ABK75665.1 | ABK70833.1 | MSMEG_1571 | MSMEG_3975 | Integral membrane protein; Identified by match to protein family HMM PF00892. | Regulatory protein, putative; Identified by match to protein family HMM PF07905. | 0.531 |
ABK75665.1 | ABK71623.1 | MSMEG_1571 | MSMEG_5407 | Integral membrane protein; Identified by match to protein family HMM PF00892. | Integral membrane protein. | 0.426 |
ABK75665.1 | ABK71821.1 | MSMEG_1571 | MSMEG_1506 | Integral membrane protein; Identified by match to protein family HMM PF00892. | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | 0.571 |