STRINGSTRING
ABK75489.1 ABK75489.1 ABK73273.1 ABK73273.1 ABK74788.1 ABK74788.1 ABK72510.1 ABK72510.1 mfpA mfpA ftsY ftsY ffh ffh ABK70569.1 ABK70569.1 ABK73328.1 ABK73328.1 rpmD rpmD rplR rplR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK75489.1Identified by match to protein family HMM PF03029. (193 aa)    
Predicted Functional Partners:
ABK73273.1
Roadblock/LC7 domain protein; Identified by match to protein family HMM PF03259.
 
 
 0.999
ABK74788.1
Conserved hypothetical protein; Identified by match to protein family HMM PF05331.
 
  
 0.996
ABK72510.1
Periplasmic sensor signal transduction histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518.
 
  
 0.980
mfpA
Conserved hypothetical protein; When present on multicopy plasmids confers increased resistance to fluoroquinolone antibiotics such as ciprofloxacin and sparfloxacin but not the quinolone nalidixic acid. Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (By similarity). Belongs to the pentapeptide repeat protein family.
  
  
 0.978
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
 0.974
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
 
 0.878
ABK70569.1
Cation ABC transporter, ATP-binding protein, putative; Identified by match to protein family HMM PF00005.
   
  
 0.755
ABK73328.1
ATPase.
      
 0.753
rpmD
Ribosomal protein L30; Identified by match to protein family HMM PF00327; match to protein family HMM TIGR01308.
   
 
 0.722
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.714
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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