STRINGSTRING
ABK72665.1 ABK72665.1 ABK71220.1 ABK71220.1 rpoB rpoB rpoC rpoC ABK74824.1 ABK74824.1 ABK71286.1 ABK71286.1 ABK76188.1 ABK76188.1 ABK69658.1 ABK69658.1 ABK73163.1 ABK73163.1 rpoA rpoA ABK75526.1 ABK75526.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK72665.1RNA polymerase sigma-F factor; Identified by match to protein family HMM PF04539; match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; match to protein family HMM TIGR02980; Belongs to the sigma-70 factor family. (250 aa)    
Predicted Functional Partners:
ABK71220.1
RsbW protein.
 
 
 0.998
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
  
 
 0.926
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.921
ABK74824.1
Stas domain, putative; Identified by match to protein family HMM PF01740.
  
 
 0.899
ABK71286.1
RsbW protein.
  
 
 0.893
ABK76188.1
Magnesium or manganese-dependent protein phosphatase; Identified by match to protein family HMM PF00072; match to protein family HMM PF07228.
  
 
 0.883
ABK69658.1
Two-component sensor protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF05227.
  
  
 0.868
ABK73163.1
Anti-anti-sigma factor; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.845
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.827
ABK75526.1
ChaB protein; Identified by match to protein family HMM PF06150.
 
  
 0.816
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.