STRINGSTRING
ABK70857.1 ABK70857.1 ABK72595.1 ABK72595.1 ABK72224.1 ABK72224.1 glyA glyA cofD cofD ABK71322.1 ABK71322.1 ABK75146.1 ABK75146.1 fbiB fbiB ABK73664.1 ABK73664.1 ABK73270.1 ABK73270.1 ABK75450.1 ABK75450.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK70857.15,10-methylenetetrahydromethanopterin reductase. (299 aa)    
Predicted Functional Partners:
ABK72595.1
5,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296.
  
 
  0.962
ABK72224.1
5,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296.
  
 
 
0.930
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.903
cofD
Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.782
ABK71322.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
    0.742
ABK75146.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
    0.735
fbiB
F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...]
 
  
 0.733
ABK73664.1
Putative oxidoreductase; Identified by match to protein family HMM PF00296.
  
    0.729
ABK73270.1
Hydride transferase 1; Identified by match to protein family HMM PF00296.
  
    0.721
ABK75450.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
    0.718
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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