node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70529.1 | ABK73574.1 | MSMEG_6767 | MSMEG_2156 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | 0.767 |
ABK70529.1 | ABK74760.1 | MSMEG_6767 | MSMEG_2469 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550. | 0.802 |
ABK70529.1 | ABK75546.1 | MSMEG_6767 | MSMEG_0159 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Formate dehydrogenase, gamma subunit; Identified by similarity to GB:CAA11233.1; match to protein family HMM PF01257. | 0.797 |
ABK70529.1 | nuoB | MSMEG_6767 | MSMEG_2062 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.967 |
ABK70529.1 | nuoC | MSMEG_6767 | MSMEG_2061 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | NADH-quinone oxidoreductase chain c; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.976 |
ABK70529.1 | nuoD | MSMEG_6767 | MSMEG_2060 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | NADH-quinone oxidoreducatase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.957 |
ABK70529.1 | nuoG | MSMEG_6767 | MSMEG_2057 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | NADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. | 0.846 |
ABK70529.1 | nuoI | MSMEG_6767 | MSMEG_2055 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | NADH-quinone oxidoreductase, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.975 |
ABK70529.1 | pks | MSMEG_6767 | MSMEG_0408 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801. | 0.966 |
ABK70529.1 | pks5 | MSMEG_6767 | MSMEG_4727 | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis. | 0.903 |
ABK73574.1 | ABK70529.1 | MSMEG_2156 | MSMEG_6767 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801. | 0.767 |
ABK73574.1 | ABK74760.1 | MSMEG_2156 | MSMEG_2469 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550. | 0.775 |
ABK73574.1 | ABK75546.1 | MSMEG_2156 | MSMEG_0159 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | Formate dehydrogenase, gamma subunit; Identified by similarity to GB:CAA11233.1; match to protein family HMM PF01257. | 0.752 |
ABK73574.1 | nuoB | MSMEG_2156 | MSMEG_2062 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.819 |
ABK73574.1 | nuoC | MSMEG_2156 | MSMEG_2061 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | NADH-quinone oxidoreductase chain c; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.835 |
ABK73574.1 | nuoD | MSMEG_2156 | MSMEG_2060 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | NADH-quinone oxidoreducatase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.816 |
ABK73574.1 | nuoG | MSMEG_2156 | MSMEG_2057 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | NADH-quinone oxidoreductase, G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. | 0.812 |
ABK73574.1 | nuoI | MSMEG_2156 | MSMEG_2055 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | NADH-quinone oxidoreductase, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.827 |
ABK73574.1 | pks | MSMEG_2156 | MSMEG_0408 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801. | 0.780 |
ABK73574.1 | pks5 | MSMEG_2156 | MSMEG_4727 | Conserved hypothetical protein; Identified by match to protein family HMM PF05368. | Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis. | 0.770 |