STRINGSTRING
ABK71838.1 ABK71838.1 ABK70244.1 ABK70244.1 dnaJ dnaJ dnaJ-2 dnaJ-2 glnA-2 glnA-2 accD accD ABK69944.1 ABK69944.1 glnA glnA ABK71940.1 ABK71940.1 ABK76235.1 ABK76235.1 ABK74955.1 ABK74955.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK71838.1MerR-family protein transcriptional regulator; Identified by match to protein family HMM PF00376; match to protein family HMM PF07739. (257 aa)    
Predicted Functional Partners:
ABK70244.1
Conserved hypothetical protein.
  
 
 0.646
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.597
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.597
glnA-2
Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
 
 
 0.517
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Identified by match to protein family HMM PF01039.
 
   0.492
ABK69944.1
Acetyl-coenzyme a carboxylase carboxyl transferase; Identified by match to protein family HMM PF01039.
 
   0.470
glnA
Glutamine synthetase, catalytic domain; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
  
 
 0.448
ABK71940.1
Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
  
 
 0.447
ABK76235.1
Glutamate--ammonia ligase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
  
 
 0.447
ABK74955.1
Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.446
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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