STRINGSTRING
ABK74802.1 ABK74802.1 metK metK trmU trmU ABK73488.1 ABK73488.1 metH metH ABK74642.1 ABK74642.1 ABK76099.1 ABK76099.1 ABK71094.1 ABK71094.1 ABK72465.1 ABK72465.1 ABK74965.1 ABK74965.1 ABK73310.1 ABK73310.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK74802.1Methionine synthase, vitamin-B12 independent; Identified by match to protein family HMM PF01717. (336 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.854
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
    0.794
ABK73488.1
Methylenetetrahydrofolate reductase family protein, putative; Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.787
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.754
ABK74642.1
Cysteine desulfurase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212.
  
  
 0.751
ABK76099.1
Acetyltransferase; Identified by match to protein family HMM PF00583.
  
    0.719
ABK71094.1
Conserved hypothetical protein; Identified by match to protein family HMM TIGR03089.
 
    0.715
ABK72465.1
Conserved hypothetical protein.
  
 
 0.688
ABK74965.1
Conserved hypothetical protein.
  
 
 0.687
ABK73310.1
Bacterial type II secretion system protein F domain; Identified by match to protein family HMM PF00482.
  
    0.669
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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