STRINGSTRING
ABK75742.1 ABK75742.1 ABK75667.1 ABK75667.1 ABK69553.1 ABK69553.1 ABK73773.1 ABK73773.1 ABK72667.1 ABK72667.1 ABK69899.1 ABK69899.1 ABK71624.1 ABK71624.1 lfrA lfrA ABK70542.1 ABK70542.1 speB speB speB-3 speB-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK75742.1Identified by match to protein family HMM PF07690. (463 aa)    
Predicted Functional Partners:
ABK75667.1
Identified by match to protein family HMM PF00581; match to protein family HMM PF00753.
  
  
 0.823
ABK69553.1
Identified by match to protein family HMM PF00753.
     
 0.819
ABK73773.1
LAO/AO transport system ATPase; Identified by match to protein family HMM PF03308; match to protein family HMM TIGR00750.
      
 0.815
ABK72667.1
Major facilitator superfamily protein MFS_1; Probably plays a role in bacterial growth and resistance to antibiotics.
 
  
 0.756
ABK69899.1
MmpL5 protein; Identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833.
      
 0.754
ABK71624.1
3-oxoacyl-[acyl-carrier-protein] reductase; Identified by match to protein family HMM PF00106.
  
    0.641
lfrA
Proton antiporter efflux pump; Energy-dependent efflux pump that contributes to drug resistance. Catalyzes the efflux of norfloxacin and several related fluoroquinolones (FQ). Contributes significantly to the intrinsic MICs for ethidium bromide and acriflavine. Overexpression confers low-level resistance to hydrophilic FQ such as ciprofloxacin, ofloxacin and levofloxacin, and to ethidium bromide, acridine, acriflavine, rhodamine 123 and some quaternary ammonium compounds. May contribute to resistance to certain beta-lactams. Probably uses the proton motive force.
  
  
 0.599
ABK70542.1
Identified by match to protein family HMM PF00106; match to protein family HMM PF01370.
  
    0.536
speB
Agmatinase; Identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family.
  
  
 0.533
speB-3
Agmatinase; Identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family.
  
  
 0.530
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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