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ABK70007.1 ABK70007.1 ABK74805.1 ABK74805.1 ABK70552.1 ABK70552.1 ABK70559.1 ABK70559.1 ABK71886.1 ABK71886.1 acsA acsA ABK73777.1 ABK73777.1 PrpE PrpE ABK74315.1 ABK74315.1 ABK73027.1 ABK73027.1 ABK70948.1 ABK70948.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK70007.1Aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (451 aa)    
Predicted Functional Partners:
ABK74805.1
Short chain dehydrogenase; Identified by match to protein family HMM PF00106.
 
 
 0.894
ABK70552.1
Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
 
  
 0.890
ABK70559.1
Peptidase C26; Identified by match to protein family HMM PF00117; match to protein family HMM PF07722.
 
  
 0.854
ABK71886.1
GntR-family protein transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF02082; match to protein family HMM PF07729.
 
    0.746
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.721
ABK73777.1
acyl-CoA synthase; Identified by match to protein family HMM PF00501.
  
 0.718
PrpE
propionate--CoA ligase; Identified by match to protein family HMM PF00501.
  
 0.718
ABK74315.1
acetoacetyl-CoA synthase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01217.
  
 0.718
ABK73027.1
Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501.
  
 0.717
ABK70948.1
acetyl-CoA synthetase; Identified by match to protein family HMM PF00501.
  
 0.716
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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