STRINGSTRING
hemG hemG hemE hemE hemH hemH ABK72276.1 ABK72276.1 ABK71061.1 ABK71061.1 ABK73730.1 ABK73730.1 hemA hemA ABK76216.1 ABK76216.1 hemC hemC hemD hemD hemB hemB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hemGProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (453 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.999
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 
 0.996
ABK72276.1
Chelatase; Identified by match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM PF07728.
  
 
 0.971
ABK71061.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06778.
 
  
 0.952
ABK73730.1
Magnesium chelatase.
  
 
 0.926
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.744
ABK76216.1
Conserved hypothetical protein.
  
    0.742
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.723
hemD
uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602.
 
  
 0.687
hemB
Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.
 
  
 0.681
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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