STRINGSTRING
aftC aftC aftA aftA aftD aftD ABK75677.1 ABK75677.1 ABK75671.1 ABK75671.1 ABK72375.1 ABK72375.1 msrB msrB ABK74534.1 ABK74534.1 ABK71134.1 ABK71134.1 ABK72840.1 ABK72840.1 ABK70327.1 ABK70327.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aftCPutative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. (430 aa)    
Predicted Functional Partners:
aftA
Membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf.
  
  
 0.977
aftD
Conserved hypothetical protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
  
  
 0.973
ABK75677.1
Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561.
 
    0.924
ABK75671.1
Probable conserved transmembrane protein.
 
  
 0.904
ABK72375.1
Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602.
  
  
 0.831
msrB
methionine-R-sulfoxide reductase; Identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family.
       0.821
ABK74534.1
Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872.
  
  
 0.817
ABK71134.1
Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602.
  
  
 0.811
ABK72840.1
Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602.
  
  
 0.810
ABK70327.1
Conserved hypothetical protein.
  
    0.776
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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