node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK72065.1 | ABK74534.1 | MSMEG_2788 | MSMEG_2787 | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | 0.799 |
ABK72065.1 | ABK75677.1 | MSMEG_2788 | MSMEG_2786 | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | 0.650 |
ABK72065.1 | aftC | MSMEG_2788 | MSMEG_2785 | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.624 |
ABK72065.1 | msrB | MSMEG_2788 | MSMEG_2784 | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | methionine-R-sulfoxide reductase; Identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family. | 0.547 |
ABK74534.1 | ABK72065.1 | MSMEG_2787 | MSMEG_2788 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | 0.799 |
ABK74534.1 | ABK75677.1 | MSMEG_2787 | MSMEG_2786 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | 0.834 |
ABK74534.1 | aftC | MSMEG_2787 | MSMEG_2785 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.817 |
ABK74534.1 | folA | MSMEG_2787 | MSMEG_2671 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.645 |
ABK74534.1 | msrB | MSMEG_2787 | MSMEG_2784 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | methionine-R-sulfoxide reductase; Identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family. | 0.664 |
ABK74534.1 | ribBA | MSMEG_2787 | MSMEG_3072 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.924 |
ABK74534.1 | ribE | MSMEG_2787 | MSMEG_3071 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Riboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187. | 0.789 |
ABK74534.1 | ribE-2 | MSMEG_2787 | MSMEG_3073 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.874 |
ABK74534.1 | ribF | MSMEG_2787 | MSMEG_2653 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; match to protein family HMM TIGR00125; Belongs to the ribF family. | 0.818 |
ABK74534.1 | ribH | MSMEG_2787 | MSMEG_6598 | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.680 |
ABK75677.1 | ABK72065.1 | MSMEG_2786 | MSMEG_2788 | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | 0.650 |
ABK75677.1 | ABK74534.1 | MSMEG_2786 | MSMEG_2787 | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | 0.834 |
ABK75677.1 | aftC | MSMEG_2786 | MSMEG_2785 | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.924 |
ABK75677.1 | msrB | MSMEG_2786 | MSMEG_2784 | Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561. | methionine-R-sulfoxide reductase; Identified by match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family. | 0.808 |
aftC | ABK72065.1 | MSMEG_2785 | MSMEG_2788 | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | ATP/GTP-binding integral membrane protein; Identified by match to protein family HMM PF03969. | 0.624 |
aftC | ABK74534.1 | MSMEG_2785 | MSMEG_2787 | Putative conserved integral membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | Putative riboflavin biosynthesis protein RibD; Identified by match to protein family HMM PF01872. | 0.817 |