node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70160.1 | ABK72709.1 | MSMEG_2792 | MSMEG_2790 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Conserved hypothetical protein. | 0.780 |
ABK70160.1 | ABK73428.1 | MSMEG_2792 | MSMEG_1537 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Conserved hypothetical protein. | 0.697 |
ABK70160.1 | ABK75774.1 | MSMEG_2792 | MSMEG_0699 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Conserved hypothetical proline rich protein. | 0.696 |
ABK70160.1 | clpP | MSMEG_2792 | MSMEG_4672 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.856 |
ABK70160.1 | clpP-2 | MSMEG_2792 | MSMEG_4673 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.856 |
ABK70160.1 | clpS | MSMEG_2792 | MSMEG_4910 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.813 |
ABK70160.1 | dnaJ | MSMEG_2792 | MSMEG_0711 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.723 |
ABK70160.1 | dnaJ-2 | MSMEG_2792 | MSMEG_4504 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.724 |
ABK70160.1 | dnaK | MSMEG_2792 | MSMEG_0709 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.695 |
ABK70160.1 | grpE | MSMEG_2792 | MSMEG_0710 | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.812 |
ABK72709.1 | ABK70160.1 | MSMEG_2790 | MSMEG_2792 | Conserved hypothetical protein. | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | 0.780 |
ABK73428.1 | ABK70160.1 | MSMEG_1537 | MSMEG_2792 | Conserved hypothetical protein. | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | 0.697 |
ABK73428.1 | clpP | MSMEG_1537 | MSMEG_4672 | Conserved hypothetical protein. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.632 |
ABK73428.1 | clpP-2 | MSMEG_1537 | MSMEG_4673 | Conserved hypothetical protein. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.633 |
ABK73428.1 | dnaJ | MSMEG_1537 | MSMEG_0711 | Conserved hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.891 |
ABK73428.1 | dnaJ-2 | MSMEG_1537 | MSMEG_4504 | Conserved hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.889 |
ABK73428.1 | grpE | MSMEG_1537 | MSMEG_0710 | Conserved hypothetical protein. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.941 |
ABK75774.1 | ABK70160.1 | MSMEG_0699 | MSMEG_2792 | Conserved hypothetical proline rich protein. | Clp amino terminal domain protein; Identified by match to protein family HMM PF02861. | 0.696 |
ABK75774.1 | clpP | MSMEG_0699 | MSMEG_4672 | Conserved hypothetical proline rich protein. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.632 |
ABK75774.1 | clpP-2 | MSMEG_0699 | MSMEG_4673 | Conserved hypothetical proline rich protein. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.638 |