STRINGSTRING
ABK70591.1 ABK70591.1 kshB kshB ABK70902.1 ABK70902.1 ksdD ksdD ABK70837.1 ABK70837.1 ABK72155.1 ABK72155.1 ABK72635.1 ABK72635.1 ABK74064.1 ABK74064.1 ABK71760.1 ABK71760.1 kshA kshA ABK73895.1 ABK73895.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK70591.1Oxygenase KshA; Identified by match to protein family HMM PF00355. (386 aa)    
Predicted Functional Partners:
kshB
Oxidoreductase, electron transfer component; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
 
 
 0.995
ABK70902.1
3-ketosteroid-delta-1-dehydrogenase; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266.
 
 
 0.991
ksdD
3-ketosteroid dehydrogenase; Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to.
 
 
 0.988
ABK70837.1
3-ketosteroid dehydrogenase; Identified by match to protein family HMM PF00890.
 
 
 0.968
ABK72155.1
Oxidoreductase, NAD/FAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
 
 
 0.966
ABK72635.1
3-ketosteroid dehydrogenase; Identified by match to protein family HMM PF00890.
 
 
  0.957
ABK74064.1
Conserved hypothetical protein.
 
    0.954
ABK71760.1
3-ketosteroid-delta4; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266.
 
  
 0.918
kshA
Rieske [2Fe-2S] domain protein; Involved in the degradation of cholesterol. Catalyzes the introduction of a 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD) to yield the 9alpha-hydroxy-1,4-androstadiene-3,17-dione (9OHADD) intermediate which spontaneously form 3-hydroxy-9,10-seconandrost- 1,3,5(10)-triene-9,17-dione (HSA) via the meta-cleavage of ring B with concomitant aromatization of ring A.
  
 
 
0.903
ABK73895.1
Biphenyl-2,3-diol 1,2-dioxygenase; Identified by match to protein family HMM PF00903.
 
  
 0.867
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.