STRINGSTRING
ABK73706.1 ABK73706.1 ABK72171.1 ABK72171.1 ABK71265.1 ABK71265.1 ABK72371.1 ABK72371.1 senX3 senX3 ABK70626.1 ABK70626.1 ABK74820.1 ABK74820.1 ABK71475.1 ABK71475.1 ABK74047.1 ABK74047.1 ABK75033.1 ABK75033.1 mprB mprB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK73706.1DNA-binding response regulator, PhoP family protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (255 aa)    
Predicted Functional Partners:
ABK72171.1
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 0.999
ABK71265.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.918
ABK72371.1
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.904
senX3
Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system.
 
 0.890
ABK70626.1
Sensor histidine kinase PhoR; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.883
ABK74820.1
KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  
0.881
ABK71475.1
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.874
ABK74047.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.868
ABK75033.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.863
mprB
Sensor histidine kinase; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
 
 
 0.840
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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